[Lilug] LILUG meeting tomorrow

Mon Aug 8 09:39:28 PDT 2016

I don't know who the speaker is, but i understand it's not set in stone

I am very interested in learning more about what you refer to as
"sociopathy or psychopathological" 'stuff' with respect to genetics.

Yesterday, i enquired with my psych-doc about genetic testing for drug
compatibility (something like genesight though it may be a different
company).  He said we'd discuss it in person on thursday.  Assuming i can
get a copy of a "dna file" from the testing, i wonder if i could plug it
into something open source and get useful information out of it.  I don't
know whether this open source software would be kind of a simulator that
"grows the dna to see what will come" or whether it is just a database that
says if you have x here and y there and z over here, statistically you are
likely to have condition w.

I want to attend tomorrow, but i have a furniture deivery "scheduled" in
the late afternoon or evening (who knows when they show up).

-Rob

On Aug 8, 2016 12:17 PM, "Robert Phelps" <bobp at buckram.org> wrote:

> Good topic.  Who's the speaker?
>
> Wanted to follow up my last post with a perhaps entirely bogus overview of
> the developmental aspects that relate to your interest.
>
> You now understand that the map from DNA-IN-ONE-CELL =>
> DNA-IN-NEXT-CELL-GENERATED-BY-THAT-CELL is controlled (in part, there's
> much more that we're learning) by histone-related exposure of regions of
> DNA in the parent cell.
>
> There appears to be a lot of significant signaling that goes on that
> determines what is exposed or what is not exposed, and from there, what
> happens with other parts of the machinery that encodes protein that, among
> other things, determines whether a particular cell will divide.
>
> You understand that some cells somehow wind up in an environment that will
> make a finger, some cells in an environment that will make T-Cells.  Some
> things are remarkably durable in organisms - the number of six fingered
> humans that are born that way is quite small - the number of humans who
> develop six fingers having been born with five fingers is, I speculate,
> likely much smaller.  T-Cells and other parts of the immune system differ
> from fingers in many ways - they do change quite remarkably based on their
> "environment."
>
> If you get a chance, you may want to read about a recent paper where some
> people (I think a group in Texas and a group in Europe, Germany perhaps)
> did a very careful mapping of brain "regions" - where they were looking at
> large numbers of 'assayable' - things that could define regions.  Their
> approach dramatically up-numbered the count for brain regions.
>
> This becomes helpful-useful in understanding sociopathy or
> psychopathological behavior.  You are aware that some heritable traits
> involve large numbers of "genes" - possibly coming into play and
> "expressing" at different times during development, where development and
> expression is known to involve chemical changes of all kinds that  can be
> responses to events that initiate outside the organism.
>
> I haven't looked directly for genetic/epigenetic literature on the
> pathological anti-social behavior that interest you.  I tend to want to
> think things through on my own before wading in.  My excuse is that I'm
> more likely to appreciate the work, etc.  It's also possible that I'm just
> lazy.
>
> I'm really very pleased that you've taken an interest in this subject.
> More CS and engineering people should be exposed to science and scientific
> research - for a lot of reasons, not the least of which is that you and may
> other people are very talented and can make contributions to the science if
> you have the time, patience and get lucky (luck is a big part of life, for
> better or worse).
>
> It's a shame that the Saopolsky lecture series is gone from the Internet
> Archive.  That because some of what he talks about apropos the relationship
> between the endocrine system and the nervous system is something that you
> would enjoy and something that I think would broaden your understanding of
> the exciting challenge you've set for yourself.
>
> More later.  I'm repeating myself.  If you've gone this far, who is the
> speaker and how'd you find him?
>
> On Mon, Aug 8, 2016 at 11:01 AM, odinson <odinson at warcloud.net> wrote:
>
>> Hi All
>>
>>         Next LILUG meeting is tomorrow, 8/9 at 8pm at CSHL Woodbury
>> campus.  Topic is open source genetics, BUT, our guest speaker has not
>> confirmed with me.  Soooo, it's possibly lightning talks.  No worries, I
>> think we're ready for anything right?
>>
>>         I'll post here if anything changes.  See you tomorrow.
>>
>> Matt
>>
>> ------------------------------------------------------------
>> -------------------
>> Matthew Newhall, M.A.Newhall at warcloud.net
>> A.S. in Computer Science, SUNY Farmingdale
>> President and founder of LILUG;  president at lilug.org,
>> http://www.lilug.org
>> My theory; Psychopaths precede the conscience,
>> http://civgene.matthewnewhall.com
>> My maker blog; "The modness", http://themodness.wordpress.com
>> Scifi book; "Thicker Than Blood"  http://www.thickerthanbloodthebook.com
>> Giselle's husband, Sebastian and Maxximus's father.
>> http://www.warcloud.net/~odinson/us/
>> "If we win another such battle against the Romans, we will be completely
>> lost."
>>         -- King Pyrrhus of Epirus
>> ------------------------------------------------------------
>> -------------------
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>
>
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